The Endometriome is a screening test that provides information about the intrauterine microbial environment. In fact, there is an important relationship between the endometrial microbiota and embryo implantation.
Specifically, in the presence of dysbiosis or pathogenic bacteria, the alteration of the endometrial microbiota can hinder the onset of pregnancy or be the cause of a miscarriage. The most prevalent endogenous bacterial species is Lactobacillus.
An important example of a pathology caused by the alteration of the endometrial microbiota is Chronic Endometritis (CE).
CE is characterized by a persistent inflammatory process affecting the endometrium and is generally asymptomatic, although in some cases it may present non-specific symptoms such as abnormal uterine bleeding, pelvic pain, or foul-smelling discharge.
It is estimated that in 39% of reproductive failures, the woman is affected by CE, with percentages rising to 60% in women with recurrent miscarriages (RPL) and 66% in women characterized by repeated failures.
It is a genetic screening test that evaluates the uterine microbial environment, specifically the optimal characteristics that allow for embryo implantation.
The Endometriome can be performed using a sample of tissue or endometrial fluid, taken at our clinic between the 15th and 25th days of the menstrual cycle or during the secretory phase in hormone replacement therapy (HRT) cycles.
Subsequently, the test involves genetic analysis using Next Generation Sequencing (NGS) conducted by the GENOMA molecular genetics laboratory in Rome, and if necessary, an appropriate corrective treatment.
The staff at CMR is here to support you through the activation of an ONLINE CONSULTATION desk, where they will answer all your questions to establish a first approach and begin an important journey together.