Genetic Compatibility Test (CGT)
The Genetic Compatibility Test (CGT) is a diagnostic test that allows us to identify the presence of genes in future parents that cause diseases that could be passed on to their children.
Every person is born with genetic characteristics that differentiate them from others and make them unique.
While most differences in DNA sequences between different people are harmless, some changes, known as genetic mutations, can make a person a carrier of a specific hereditary genetic disease.
Carriers of genetic diseases are typically healthy individuals, completely symptom-free and unaware of their risk of passing such a "mistake" in DNA to their children.
Thus, the CGT allows the couple to learn, through the analysis of their DNA, whether they are carriers of serious genetic diseases and what the risk is of passing them on to their children.
The test involves a simple blood sample that will be taken at the CMR, after which the sample will be sent to the molecular genetics laboratory.
This allows for a multiplex analysis for various hereditary genetic diseases, including the most common ones in the Italian population, such as Cystic Fibrosis, Sickle Cell Anemia, Thalassemia, and Hereditary Deafness.
The examination can be performed on a single individual or, preferably, on both partners of the couple.
This type of analysis can be performed by any couple before trying to conceive and is particularly interesting for those at higher risk of consanguinity (family ties) because there is a greater likelihood of sharing mutations in the same gene.
If both parents are carriers of a specific mutation, the probability in each pregnancy of having unhealthy children is 25% (1 in 4).
In these cases, it is necessary to undergo a cycle of in vitro fertilization, where the generated embryos will undergo preimplantation genetic diagnosis, allowing for the analysis of which of them are not affected by the mutation and therefore which can be transferred to the patient.
The staff at CMR is here to support you through the activation of an ONLINE CONSULTATION desk, where they will answer all your questions to establish a first approach and begin an important journey together.